Colorado Code
Part 1 - General Provisions
§ 12-280-125. Substitution of Prescribed Drugs and Biological Products Authorized - When - Conditions













(A) The FDA has determined that the biological product to be substituted is interchangeable with the prescribed biological product; and
(B) The practitioner has not indicated, in the manner described in subsection (2) of this section, that the pharmacist shall not substitute an interchangeable biological product for the prescribed biological product.


(I) Initialing by hand or electronically a preprinted box that states "dispense as written" or "DAW";
(II) Signing by hand or electronically a preprinted box stating "do not substitute" or "dispense as written"; or
(III) Orally, if the practitioner communicates the prescription orally to the pharmacist.









Source: L. 2019: Entire title R&RE with relocations, (HB 19-1172), ch. 136, p. 1470, § 1, effective October 1. L. 2021: (1)(a.5) added and IP(2)(a), (3)(b), and (5) amended, (SB 21-094), ch. 314, p. 1933, § 14, effective September 1.
Editor's note: This section is similar to former § 12-42.5-122 as it existed prior to 2019.

Structure Colorado Code

Colorado Code

Title 12 - Professions and Occupations

Article 280 - Pharmacists, Pharmacy Businesses, and Pharmaceuticals

Part 1 - General Provisions

§ 12-280-101. Public Interest - Rules

§ 12-280-102. Applicability of Common Provisions

§ 12-280-103. Definitions - Rules

§ 12-280-104. State Board of Pharmacy - Creation - Subject to Review - Repeal of Parts

§ 12-280-105. Membership of Board - Removal - Compensation - Meetings - Repeal

§ 12-280-106. Veterinary Pharmaceutical Advisory Committee - Creation - Appointments - Rules - Repeal

§ 12-280-107. Rules

§ 12-280-108. Powers and Duties - Rules

§ 12-280-109. Drugs, Devices, and Other Materials

§ 12-280-110. Publications

§ 12-280-111. Malpractice Claims Information - Not Public - Exception

§ 12-280-112. Fees

§ 12-280-113. Approval of Schools

§ 12-280-114. Licensure, Certification, or Registration - Applicability - Applications - Licensure and Certification Requirements - Rules

§ 12-280-115. Exemptions From Licensure - Hospital Residency Programs - Home Renal Dialysis - Research Companies

§ 12-280-115.5. Certification of Pharmacy Technicians - Requirements - Provisional Certification - Criminal History Record Check - Rules

§ 12-280-116. Expiration and Renewal of Licenses, Certifications, or Registrations

§ 12-280-117. Continuing Education - Exceptions - Inactive Status

§ 12-280-117.5. Continuing Education for Pharmacy Technicians - Exceptions - Inactive Status

§ 12-280-118. Prescription Drug Outlet Under Charge of Pharmacist - Rules

§ 12-280-119. Registration of Facilities - Rules

§ 12-280-120. Compounding - Dispensing - Sale of Drugs and Devices - Rules - Definition

§ 12-280-121. Compounding Drugs for Office Use by a Veterinarian - Rules - Definitions

§ 12-280-122. Limited Authority to Delegate Activities Constituting Practice of Pharmacy to Pharmacy Interns or Pharmacy Technicians

§ 12-280-123. Prescription Required - Exception - Dispensing Opiate Antagonists - Selling Nonprescription Syringes and Needles

§ 12-280-124. Labeling - Rules

§ 12-280-125. Substitution of Prescribed Drugs and Biological Products Authorized - When - Conditions

§ 12-280-125.3. Pharmacists' Authority - Minor Prescription Adaptions

§ 12-280-125.5. Pharmacists' Authority to Dispense Chronic Maintenance Drugs - Rules - Liability

§ 12-280-125.7. Pharmacists' Authority to Prescribe and Dispense Hiv Infection Prevention Drugs - Definitions - Rules

§ 12-280-126. Unprofessional Conduct - Grounds for Discipline

§ 12-280-127. Disciplinary Actions

§ 12-280-128. Judicial Review

§ 12-280-129. Unlawful Acts - Civil Fines

§ 12-280-130. Unauthorized Practice - Penalties

§ 12-280-131. New Drugs - When Sales Permissible

§ 12-280-132. Advertising of Prescription Drug Prices

§ 12-280-133. Nonresident Prescription Drug Outlet - Registration

§ 12-280-133.5. Nonresident 503b Outsourcing Facility - Registration - Requirements - Denial, Revocation, or Suspension - Rules

§ 12-280-133.7. Third-Party Logistics Providers - Registration - Denial, Revocation, or Suspension - Rules

§ 12-280-134. Records

§ 12-280-135. Unused Medication - Licensed Facilities - Correctional Facilities - Reuse - Definitions - Rules

§ 12-280-136. Confidential Agreement to Limit Practice

§ 12-280-137. Investigations of Suspicious Drugs

§ 12-280-138. Patient Counseling - Pharmacists Required to Perform - Patient May Decline - Rules

§ 12-280-139. Insulin Affordability Program - Record Keeping - Reimbursement - Definitions

§ 12-280-140. Emergency Prescription Insulin Supply - Eligibility - Record Keeping - Definition